PT  - JOURNAL ARTICLE
AU  - Kakimoto, Tatsuo
TI  - CKI1, a Histidine Kinase Homolog Implicated in Cytokinin Signal Transduction
AID  - 10.1126/science.274.5289.982
DP  - 1996 Nov 08
TA  - Science
PG  - 982--985
VI  - 274
IP  - 5289
4099  - http://science.sciencemag.org/content/274/5289/982.short
4100  - http://science.sciencemag.org/content/274/5289/982.full
SO  - Science1996 Nov 08; 274
AB  - Although cytokinin plays a central role in plant development, little is known about cytokinin signal transduction. Five Arabidopsis thaliana mutants that exhibit typical cytokinin responses, including rapid cell division and shoot formation in tissue culture in the absence of exogenous cytokinin, were isolated by activation transferred DNA tagging. A gene, CKI1, which was tagged in four of the five mutants and induced typical cytokinin responses after introduction and overexpression in plants, was cloned. CKI1 encodes a protein similar to the two-component regulators. These results suggest that CKI1 is involved in cytokinin signal transduction, possibly as a cytokinin receptor.