PT  - JOURNAL ARTICLE
AU  - Horner, Andreas
AU  - Pohl, Peter
TI  - Comment on “Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins”
AID  - 10.1126/science.aap9173
DP  - 2018 Mar 30
TA  - Science
PG  - eaap9173
VI  - 359
IP  - 6383
4099  - http://science.sciencemag.org/content/359/6383/eaap9173.short
4100  - http://science.sciencemag.org/content/359/6383/eaap9173.full
SO  - Science2018 Mar 30; 359
AB  - Tunuguntla et al. (Reports, 25 August 2017, p. 792) report that permeation of single-file water occurs faster through carbon nanotubes than through aquaporins. We show that this conclusion violates fundamental thermodynamic laws: Because of its much lower activation energy, aquaporin-mediated water transport must be orders of magnitude faster. Leakage at the nanotube-membrane interface may explain the discrepancy.