RT Journal Article
SR Electronic
T1 Comment on “Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins”
JF Science
JO Science
FD American Association for the Advancement of Science
SP eaap9173
DO 10.1126/science.aap9173
VO 359
IS 6383
A1 Horner, Andreas
A1 Pohl, Peter
YR 2018
UL http://science.sciencemag.org/content/359/6383/eaap9173.abstract
AB Tunuguntla et al. (Reports, 25 August 2017, p. 792) report that permeation of single-file water occurs faster through carbon nanotubes than through aquaporins. We show that this conclusion violates fundamental thermodynamic laws: Because of its much lower activation energy, aquaporin-mediated water transport must be orders of magnitude faster. Leakage at the nanotube-membrane interface may explain the discrepancy.