Table 2

Haplotypes defined by the four independent SNPs, classical HLA alleles, and amino acids associated with host control in the European sample. Haplotypes are ordered by the estimated odds ratio, where the most common haplotype was taken as reference (OR = 1). P values are for each haplotype tested against all other haplotypes. Only haplotypes with >1% frequency are listed, accounting for >85% of haplotype diversity. HLA-A alleles were excluded to limit the number of haplotypes. See (33).

rs3131018HLA-Crs9264942HLA-Brs4418214rs2395029FrequencyORP value
Classical304Classical6263677097
CMCB*57:01GEMSVCG0.0607.051.5E–26
CMCB*52:01RESNTTT0.0116.324.2E–05
CVCB*27:05RECKNCT0.0513.411.3E–10
CMCRESNTTT0.0242.781.3E–03
CCw*08:02MCB*14:02RNCNWTT0.0302.586.0E–03
CMCRNSNRTT0.0212.164.2E–02
CVCRNFNTTT0.0212.024.6E–01
CMCRNCNRTT0.0251.581.7E–01
CVCRESNSTT0.0121.504.5E–01
AMCRESNRTT0.0671.386.5E–01
CMTRNFNTTT0.0201.298.9E–01
AMCRNSNRTT0.0161.031.7E–01
CVTRESNRTT0.168(reference)1.6E–03
CMCRESNRTT0.0220.984.4E–01
AVTRESNRTT0.0180.876.0E–02
CCw*07:01VTRNSNRTT0.0160.809.5E–02
CCw*07:01VTB*08:01RNFNSTT0.0850.796.0E–05
CVTRNYQTTT0.0180.673.3E–02
ACw*07:02VTB*07:02RNYQSTT0.1160.653.2E–08
AVTB*35:01RNFNRTT0.0500.514.3E–06
AVTRNFNRTT0.0170.294.1E–05