Table 1

NP-binding and mIgG1-expressing cell populations in the spleen of wild-type and IgG1Δ tail/ Δ tailmice before and after immunization with NP-CG. We analyzed 105 cells as described in Fig. 4. Results are expressed as percentages of total spleen cells. Mean values and standard deviations are shown, except for the results obtained at day 49.

Day (number of animals) NP+mIgG1+All mIgG1+
Wild-type mice
0* (4) <0.010.15  ±  0.05
14 (6) 0.18 ± 0.080.90  ±  0.18
28 (5) 0.08 ± 0.03 0.72  ±  0.21
49 (2) 0.05, 0.05 0.53, 0.58 
IgG1 Δ tail/ Δ tail mice
0 (4) <0.01 0.01  ±  0.01
14 (6)0.02 ± 0.01 0.08  ±  0.07
28 (5) 0.01 ± 0.010.06  ±  0.03
49 (2) 0.01, <0.01       0.02, 0.02
  • * Results from unimmunized mice.