Table 1

Recovery of Tg cells, 1 week after transfer into various irradiated hosts, that differed in MHC class I or antigen presentation. Mice were injected with 1 × 106 Tg cells. Results represent the absolute number of Tg cells (×10−5) recovered in host mice and are the mean of two experiments (male mice) or the mean ± SE of three to five independent experiments in other mice (two mice per experiment). Mice injected with naı̈ve and memory cells were studied simultaneously. KO, knockout.

♂ CD8 KO♀ CD8 KO♀ H-2DbKO♀ H-2Db × β2M KO
Naı̈ve
134.54  ± 0.60.3  ± 0.10.7  ± 0.3
Memory
166.118.1  ± 2.36.6  ± 1.51.0  ± 0.3