Recovery of B6 Ly5.1 T cells, 1 week after transfer into various irradiated hosts. Host mice were injected simultaneously with 1 × 106 CD8+ and 2 × 106 CD4+ LN T cells from Ly5.1+ B6 donors. Results represent the absolute numbers (×10−5) of CD8+ and CD4+ donor T cells recovered in the different hosts in a single experiment. Similar results were obtained in three other experiments (37).
♀ CD8 KO | ♀ H-2Kb KO | ♀ H-2DbKO | ♀ H-2Db × β2M KO |
---|---|---|---|
CD4+ | |||
9 | 15.5 | 8.5 | 28.6 |
CD8+ | |||
7.1 | 6.6 | 5.7 | 1.5 |