Table 1

G-C skew for each of the three codon positions, calculated separately for the coding strand of 2357 forward genes (whose coding strand is the leading strand) and 1929 backward genes (whose coding strand is the lagging strand). The net skew attributable to replication direction is the difference between the values for the forward and the backward genes divided by 2.

PositionForward genes Backward genes Average G-C skew Net G-C skew attributable to replication direction
119.41 16.08 17.74 1.66
2 –9.34 –11.79–10.57 1.22
3 7.99 –0.48 3.75 4.23
Average 6.02 1.27 3.642.37