Table 4

Distribution of E. coli proteins among 22 functional groups (simplified schema).

Functional class Number Percent of total
Regulatory function 45 1.05
Putative regulatory proteins 133 3.10
Cell structure 182 4.24
Putative membrane proteins 13 0.30
Putative structural proteins 42 0.98
Phage, transposons, plasmids 872.03
Transport and binding proteins 281 6.55
Putative transport proteins 146 3.40
Energy metabolism243 5.67
DNA replication, recombination, modification, and repair 115 2.68
Transcription, RNA synthesis, metabolism, and modification 55 1.28
Translation, posttranslational protein modification 182 4.24
Cell processes (including adaptation, protection) 188 4.38
Biosynthesis of cofactors, prosthetic groups, and carriers 103 2.40
Putative chaperones 9 0.21
Nucleotide biosynthesis and metabolism58 1.35
Amino acid biosynthesis and metabolism 1313.06
Fatty acid and phospholipid metabolism 48 1.12
Carbon compound catabolism 130 3.03
Central intermediary metabolism 188 4.38
Putative enzymes 2515.85
Other known genes (gene product or phenotype known) 260.61
Hypothetical, unclassified, unknown 163238.06
Total 4288 100.00*
  • * Total of these rounded values is 99.97%.