Table 3

Nucleotide sequences of four isolates from resting CD4+ T cells of patients on HAART. Sequences at codons associated with resistance to IDV for patients who received IDV are shown. Dashes indicate identity with the consensus sequence shown in the top row. Procedures used are described in the legend to Table 2.

PatientProtease inhibitor10 ctc/L20 aag/K24 tta/L46 atg/M54 atc/I71 gct/A82 gtc/V84 ata/I90 ttg/L
14IDV–––––––––––––––––––––––––––
18IDV––––––c––/Q––––––––––––––––––
21IDV––t/L––––––––––––––––––––––––
22IDV–––––––––––––––––––––––––––
Known resistance mutations I, R, VM, RII, LVT, VA, F, T, VVM