Table 4

Nucleotide sequences of 12 isolates from resting CD4+ T cells of patients on HAART. Sequences at other codons where there are polymorphisms not associated with protease inhibitor resistance are shown. Dashes indicate identity with the consensus sequence shown in the top row. Procedures used are described in the legend to Table 2.

Patient (isolate)19 cta/L37 aat/N41 aga/R62 ata/I77 gta/V93 att/I
9 (5M1)––––g–/S–a–/K–––a––/I–––
9 (5M2)––––g–/S–a–/K–––––––––
11* ––––––––––––––––––
13* ––––––––––––––––––
14 g––/V–––––––––a––/Ic––/L
16* ––––––––––––––––––
18 –––––––a–/K–––a––/Ic––/L
19 ––––––––––––––––––
20 ––––g–/S–a–/K––––––c––/L
21* ––––––––––––––––––
22 ––––g–/S–a–/Kg––/V––––––
Known I, Q, V, T,SK, EVIL, V
polymorphisms F
  • * These sequences are distinguishable on the basis of mutations at other codons, including substitutions at the third position of several codons.