Table 1

Cell viability after treatment with TNF-α and actinomycin D. Cell lines lacking specific IFN signaling components were treated (6) with Human TNF-α and actinomycin D for 18 hours and assayed by exclusion of trypan blue.

Cell line Missing protein Viable cells (%)
2fTGHNone 8
U1ATYK2 9
U2A p48 15
U3A STAT182
U3X STAT1 84
U4A JAK1 8
U5A IFNAR22
U6A STAT2 1
2C4 None 12
γ2AJAK25