THE WORLD OF NUCLEAR TRANSPORTERS
Yeast ProteinHomologsFunction
Karyopherin αImportin α (Kap α)Helps import proteins with NLS sequences
Karyopherin β1 (Kap95)Importin β (Kap β1)Imports NLS proteins, complexed with karyopherin α (importin α)
Karyopherin β2 (Kap104)transportin (Kap β2)Imports mRNA-binding proteins, such as hnRNPA1
Karyopherin β3 (PSE1, Kap121)Kap β3Imports ribosomal proteins
Karyopherin β4 (Kap123)Imports ribosomal proteins
*SXM1 (Kap108)Imports proteins involved in processing tRNA and possibly mRNA
*MTR10 (Kap111)Imports and possibly exports mRNA-binding proteins
*CSE1CASExports karyopherin α (importin α)
*NMD5Ran BP7, Ran BP8Unknown
*LOS1Possibly transports tRNA
*MSN5Unknown
*CRM1, XPO1 (Kap124)ExportinExports proteins with leucine-rich export sequences
*PDR6Unknown
*YGL241WUnknown
*YPL125WUnknown
  • * Members of the karyopherin β4 family