Table 1

Genotype of the offspring obtained by the intercross of IKK2+/– mice. Embryos were genotyped by PCR amplification with DNA extracted from the yolk sac and primers c, d, and e (Fig. 1A) (8). Detection of heartbeat was used to determine the viability of the embryos. P0, postnatal day 0; dash, data not available.

StageGenotypeTotal
+/++/−−/−
AliveDead
E12 33 1 0 7
E12.5 6 13 101 30
E13 9 24 9 5 47
E13.5 713 4 4 28
E14 7 6 0 3 16
E14.5 4 5 0 4 13
P0 31 56 087