Table 1

Blood cell numbers inPI3Kγ −/− mice. Seven- to 12-week-oldPI3Kγ +/− (n = 5) andPI3Kγ −/− (n = 5) littermate mice were used. Bold numbers indicate statistically significant differences between PI3Kγ +/− andPI3Kγ −/− mice (Mann-Whitney Utest; P < 0.05). Values are given as the mean ± SEM. WBC, white blood cells.

ParameterPI3Kγ+/−PI3Kγ−/−
Total WBC (×103/μl)3.10 ± 0.445.98 ± 1.30
Lymphocytes (×103/μl)2.42 ± 0.383.81 ± 1.10
Lymphocytes (% in WBC)77.8 ± 3.5754.1 ± 7.92
Neutrophils (×103/μl)0.45 ± 0.101.72 ± 0.60
Neutrophils (% in WBC)14.3 ± 2.2027.8 ± 6.47
Monocytes (×103/μl)0.05 ± 0.010.19 ± 0.06
Monocytes (% in WBC)1.82 ± 0.262.96 ± 0.52
Eosinophils (×103/μl)0.09 ± 0.020.60 ± 0.16
Eosinophils (% in WBC)2.94 ± 0.4410.4 ± 2.09
Basophils (×103/μl)0.02 ± 0.010.02 ± 0.01
Basophils (% in WBC)0.54 ± 0.070.46 ± 0.19
Erythrocytes (×109/μl)9.49 ± 0.139.06 ± 0.38
Platelets (×107/μl)120 ± 5.2595.9 ± 5.55