Table 2

A comparison of D. melanogaster, C. elegans, and S. cerevisiae protein sequences to each other and to mammalian sequences (64). This table reports the number and percent of fly, worm, or yeast query sequences with similarities less than the indicated E value cutoffs. For example, in the “Fly vs. Yeast” comparison, 3986 or 28.1% of fly proteins have a similarity with a yeast protein with an E value less than 1 × 10–10. EST E values are not directly comparable to protein E values, because the resulting alignments are shorter.

No similarity E > 10−4E < 10−10E < 10−20E < 10−50E < 10−100
(n)(%)(n)(%)(n)(%)(n)(%)(n)(%)
Fly vs.
Yeast817757.6398628.1267718.912668.95043.6
Worm511036.0674347.5518036.5283219.911978.4
Mammalian583341.1703249.5583741.1358025.2177212.5
Mammalian ESTs538637.9732951.6535237.7177512.51100.8
Worm vs.
Yeast1254168.0358219.4237812.911066.04012.2
Fly860346.7713838.8542829.5288015.612296.7
Mammalian1015255.1655035.6499927.1278215.112116.6
Mammalian ESTs1035456.2600532.6400021.711706.4680.4
Yeast vs.
Fly261441.9256441.0191030.6102116.44086.5
Worm276244.2235837.8173027.788214.13485.6
Mammalian323051.7234037.5180228.999215.94296.9
Mammalian ESTs310649.7231937.1155324.95038.1180.3