Table 2

Numbers of mice developing scrapie after i.p. inoculation.

Mouse lineTreatment Beginning of treatment*Mice succumbing to scrapie Days to terminal disease (mean ± SD)
Prnp 0/0 0/5
C57BL/6 4/4 (206 ± 2)
C57BL/6 huIg +1 5/5 205, 211, 211, 214, 214
(211 ± 3)
C57BL/6 LTβR-Ig +13/3 223, 223, 263 (236 ± 19)
C57BL/6 LTβR-Ig −12/3 256, 256, >340
  • * Week relative to inoculation.

  • From (13).