Table 2

Loss of lip-1(+) function allows neighboring VPCs to adopt the 1° fate.

RowGenotype*% EGL-17::GFP expression
P3.pP4.pP5.pP6.pP7.pP8.pNo.
1 Wild-type 00010000>50
2 lip-1(lf) 0001000041
3 lin-15(rf) 2571010047924
4 lin-15(rf); lip-1(lf) 606040100308730
5 let-60(gf) 0601000333
6 let-60(gf) lip-1(lf) 94553100456253
7 [HS-mpk-1(+)] 0001000040
8 [HS-mpk-1(+)]; lip-1(lf) 01944100504432
  • * Alleles used: lip-1(zh15),lin-15(n309), let-60(n1046gf),gaIs36[HS-mpk-1(+), EF1α-D-mek(+),unc-30(+)]. In addition, these strains carried theayIs4[egl-17::gfp] reporter transgene.

  • The frequency at which EGL-17::GFP expression was observed in each VPC is indicated as a percentage.