Table 1

Dates of deployment of representative antibiotics and herbicides, and the evolution of resistance. [Source (75)]. EVOLUTION OF RESISTANCE TO ANTIBIOTICS AND HERBICIDES

Antibiotic or herbicideYear deployedResistance observed
Antibiotics
Sulfonamides1930s1940s
Penicillin 1943 1946
Streptomycin 1943 1959
Chloramphenicol 19471959
Tetracycline 1948 1953
Erythromycin1952 1988
Vancomycin1956 1988
Methicillin1960 1961
Ampicillin 1961 1973
Cephalosporins 1960s late 1960s
Herbicides
2,4-D 1945 1954
Dalapon 19531962
Atrazine 1958 1968
Picloram 1963 1988
Trifluralin 1963 1988
Triallate 1964 1987
Diclofop 1980 1987