MicroRNA gene products in Caenorhabditis elegans.
Gene | Source* | Orthologs†Expression‡§| | Develop-ment¶ |
---|---|---|---|
mir-1 | cDNA | C‡ § |Dm‡Hs‡ | Unif |
mir-2 | cDNA | C‡ § |Dm‡ | L1 |
mir-42 | cDNA | C‡ | | L1 |
mir-43 | cDNA | C‡ § | | L1 |
mir-52 | cDNA | C‡ § | | L1 |
mir-58 | cDNA | C‡ | | Unif |
mir-60 | cDNA/In | C| | L1 |
mir-62 | cDNA | C‡ § | | L1 |
mir-72 | cDNA | C‡ | | L1 |
mir-80 | cDNA | C‡ § | | Unif |
mir-81 | cDNA | C‡ | | L1 |
mir-87 | cDNA | C‡ § |Dm Hs | L1 |
mir-88 | In | C| | Unif |
mir-89 | In | C| | NT |
mir-90 | cDNA | C‡ | | L1 |
↵* Identified by screening a size-selected cDNA library (cDNA) or by informatics (In).
↵† Predicted by BLAST (15) and mfold (11, 12). C, C. elegans; Dm,Drosophila melanogaster; Hs, Homo sapiens.
↵‡ Expression of an ∼22-nt RNA confirmed by Northern blot.
↵§ The ∼22-nt transcript confirmed to be single-stranded using probes to both ends of the predicted stem loop.
↵| Expression of an ∼65-nt predicted stem-loop RNA confirmed by northern blot.
↵¶ Stage of C. eleganslarval development (L1 through L4) when the indicated transcript(s) appear most abundant. Unif, uniform expression; less than twofold change in level; NT, developmental profile not tested.