Table 2

Molecular composition of cell-matrix adhesions.

MoleculeAntibody usedFocal adhesionFibrillar adhesion3D-matrix adhesion
α5 integrinmAb11 (human), * ++
5H10-27 (mouse)
β1integrin9EG7+++
β3integrinVI-PL2+
FibronectinR745* ++
α-actininBM-75.2+±+
F-actin(phalloidin)+++
Talin4392+++
TensinT13820+++
VinculinVII F9B11++
Phosphotyrosine4G10++
FAK4.47++
FAK397 44-624+
Paxillin394++
Paxillin31 44-720++
  • * Except at the periphery of the structure.