Table 1

daf-2 allelic variation for hypoxia resistance (Hyp). Animals were raised at 20°C except sa187, e1369, e979,which were raised at 15°C then shifted to 20°C 2 days before testing. Percent dead is reported as means ± SEM per trial. Adults 2 days post L4 were exposed to <0.3% oxygen at 28°C for 20 hours then scored after a 24-hour recovery period. Each trial was a completely independent experiment done on a different day.

GenotypePercent deadTrials (n)Animals (n)
+/+95.5 ± 1.2262568
daf-2(e1370) 3.6 ± 1.3* 26835
daf-2(sa219) 4.6 ± 2.4* 4699
daf-2(m579) 8.6 ± 3.8* 5110
daf-2(e1369) 46.4 ± 15.6* 4185
daf-2(m596) 47.0 ± 3.6* 4210
daf-2(sa187) 53.3 ± 6.3* 5318
daf-2(e979) 55.6 ± 12.4* 4330
daf-2(e1391) 59.0 ± 11.7* 5174
daf-2(e1368) 77.3 ± 7.74344
daf-2(sa229) 80.1 ± 10.66547
daf-2(e1365) 87.9 ± 6.74330
daf-2(m577) 90.9 ± 6.73199
daf-2(e1371) 95.8 ± 2.44292
  • * P < 0.01 versus wild type by Mann-Whitney test.