ANTIRETROVIRAL DRUGS APPROVED BY U.S. FDA FOR HIV
Generic NameAdult dose (pills/day)TargetManufacturerApproval date
AZT (zidovudine)2RTGlaxoSmithKlineMarch '87
ddI (didanosine)1-4RTBristol-Myers SquibbOctober '91
ddC (zalcitabine)3RTHoffmann-La RocheJune '92
d4T (stavudine)2RTBristol-Myers SquibbJune '94
3TC (lamivudine)2RTGlaxoSmithKlineNovember '95
saquinavir16-18ProteaseHoffmann-La RocheDecember '95
ritonavir12ProteaseAbbott LaboratoriesMarch '96
indinavir6ProteaseMerck & Co. Inc.March '96
nevirapine2RTBoehringer IngelheimJune '96
nelfinavir9-10ProteaseAgouron PharmaceuticalsMarch '97
delavirdine6RTPharmacia & UpjohnApril '97
AZT and 3TC2RTGlaxoSmithKlineSeptember '97
efavirenz1RTDuPont PharmaceuticalsSeptember '98
abacavir2RTGlaxoSmithKlineDecember '98
amprenavir16ProteaseGlaxoSmithKlineApril '99
lopinavir and ritonavir6ProteaseAbbott LaboratoriesSeptember '00
abacavir, AZT, 3TC2RTGlaxoSmithKlineNovember '00
tenofovir1RTGilead Sciences Inc.October '01