Table 1
  • * Has additional four-node motif: (X→Z, W; Y→Z, W; Z→W), N real = 150,N rand = 85 ± 15, Z = 4.

  • Has additional four-node motif: (X→Y, Z; Y→Z; Z→W), N real = 204,N rand = 80 ± 20, Z = 6. The three-node pattern (X→Y, Z; Y→Z; Z→Y) also occurs significantly more than at random. It is not a motif by the present definition because it does not appear with completely distinct sets of nodes more than U = 4 times.

  • Has additional four-node motif: (X→Y; Y→Z, W; Z→X; W→X), N real = 914,N rand = 500 ± 70, Z = 6.

  • § Has two additional three-node motifs: (X→Y, Z; Y→Z; Z→Y), N real = 3e5,N rand = 1.4e3 ± 6e1,Z = 6000, and (X→Y, Z; Y→Z),N real = 5e5,N rand = 9e4 ± 1.5e3,Z = 250.