Table 2 Enrichment of genomic annotations among esQTLs and psQTLs.

Enrichments were evaluated by a continuous test using QTL results from the conditional model (see supplementary materials). Columns (from left to right) describe the annotation being considered, the number of SNPs matching this annotation, the set of SNPs used as background for the corresponding test, and the enrichment P values for psQTLs and esQTLs, respectively.

AnnotationNo. of SNPsBackgroundProteinRNA
Exonic12,568Intergenic2.8 × 10−142.3 × 10−21
5′ UTR6,488Intergenic3.2 × 10−55.9 × 10−19
3′ UTR15,139Intergenic2.0 × 10−61.7 × 10−16
Intronic628,591Intergenic7.1 × 10−32.9 × 10−38*
Nonsynonymous2,099Exonic5.7 × 10−39.7 × 10−2
Ribo SNitch414Exonic5.2 × 10−22.5 × 10−2
Acetylation site22Nonsynonymous3.2 × 10−20.62

*Depletion relative to background.